Preimplantation genetic testing for aneuploidy, or PGT-A, may increase IVF success
Knowledge empowers our patients facing the many unknowns in a fertility journey. For those undergoing IVF, the difficult decision of which embryo to transfer can become clearer, thanks to preimplantation genetic testing for aneuploidy, or PGT-A. PGT in Connecticut is increasing success rates for many patients, so it’s important to understand this option when planning an IVF cycle.
PGT-A can yield important genetic information, showing if an embryo has an abnormal chromosome count, known as aneuploidy. Often, an embryo with aneuploidy does not implant, but if it does, a miscarriage could result. If an aneuploid embryo develops to term, a baby could be born with a chromosomal disorder, such as Down syndrome, Fragile X syndrome or Trisomy 13.
Our fertility expert Dr. Andrew Levi consults with IVF patients considering genetic testing at Park Avenue Fertility and Reproductive Medicine. Dr. Levi takes time to customize recommendations for those considering PGT in Connecticut.
Numbers count with PGT-A
Preimplantation genetic testing for aneuploidy can aid the embryo selection process. A normal chromosome count is 46, which includes 23 chromosomes from the mother and 23 from the father. The chromosome count of an aneuploid embryo deviates from that number, with either too many or too few chromosomes present in its DNA.
This genetic testing enables potential parents to select a chromosomally normal embryo to transfer. As a result, undergoing PGT in Connecticut could increase the chances of successful IVF treatment at Park Avenue Fertility.
In addition to learning about each embryo’s chromosome count, some potential parents want to know the sex of their baby, which also is possible with preimplantation genetic testing for aneuploidy.
For those considering this cutting-edge technology, there are multiple steps.
- A small biopsy of a few cells is carefully taken from each embryo created through IVF, which leaves them unharmed.
- The IVF laboratory sends the cell samples to a specialized genetics lab for evaluation.
- The embryos are cryopreserved and securely stored.
Who needs preimplantation genetic testing for aneuploidy?
The decision to undergo PGT-A is an individual one, best discussed with Dr. Levi, who is double board certified in reproductive endocrinology and infertility as well as obstetrics and gynecology. He will thoroughly discuss this testing to see if it’s right for you.
Dr. Levi strongly encourages this testing for some patient groups as part of their IVF cycle.
- Women older than 35 who face a decline in the quantity and quality of their eggs with age
- Women who have had multiple failed IVF cycles
- Women who have experienced repeated miscarriages
- Patients who have unexplained infertility
- Patients with a family history of chromosome disorders
Other types of PGT are also available to dive even deeper into embryo genetics, detecting whether each embryo is affected by genetic disorders carried by its parents.
Understandably, the IVF process can feel overwhelming, but preimplantation genetic testing for aneuploidy makes decision-making easier. The team at Park Avenue Fertility welcomes your questions and sets high standards for customized care to calm your concerns. Contact us to learn more about PGT in Connecticut.